Honolulu, on the island of Oahu’s south shore, is capital of Hawaii and gateway to the U.S. island chain. The Waikiki neighborhood is its center for dining, nightlife and shopping, famed for its iconic crescent beach backed by palms and high-rise hotels, with volcanic Diamond Head crater looming in the distance. Sites relating to the World War II attack on Pearl Harbor include the USS Arizona Memorial.

Water and fire reign here: This is a land of verdant rain forests bisected by sparkling falls. But the fiery element flares along the volcanic coast of Kohala and the roaring furnace of the Kilauea volcano: Lava has continued to seep from the crater since its last eruption in 1983.

Nature is Hilo’s blessing, as well as its challenge. The beautiful crescent bay served as a funnel to two major tsunamis that battered the city—tragedies that are never forgotten and hopefully never repeated. (Hilo’s Pacific Tsunami Museum remains a leader in safety education.)

Once a busy fishing and farming area, Hilo blossomed into a commercial center for the sugarcane industry in the 1800s. Today’s town—its waterfront rebuilt since the last destructive wall of water in 1960—flourishes as a hub of galleries, independent shops, farmers markets and homegrown destination restaurants. A world-class astronomy center has joined this mix, underlining the awe unfolding through the telescopes atop Mauna Kea (the world’s tallest peak from base to summit, outstripping Everest by 1,363 meters, or 4,472 feet!). Meanwhile, leafy Banyan Drive celebrates more earthbound stars with its arboreal Walk of Fame. Look up, look down: Wherever you glance, Hilo looks good.

Once the playground of Hawaii’s royalty, Kona is synonymous with the famous coffee that grows on the slopes of dormant Hualalai. Here, too, is Parker Ranch, the largest privately owned ranch in the U.S. Sample shore excursions: Kona Outrigger Canoe Adventure; Parker Ranch; Big Island Helicopter Spectacular.

This sunny port on the Baja Peninsula gives you a taste of festive Mexico. Get ready for mariachi music, whale watching and fine wines from grapes grown in Mexico’s principal wine region, just south of town. Sample shore excursion: Folklore of Mexico.

Easygoing San Diego embodies the Southern California surfer town fantasy, with its more than 300 days of sun, mild year-round temperatures and accessible, sporty pastimes and tourist attractions. Cruise to San Diego and hike the Torrey Pines State Natural Reserve to get a glimpse of whale migrations, go sailing in the bay and, of course, surf the famous swells of Del Mar, Oceanside and La Jolla (among many other superb spots). Cruise from San Diego and explore the sixth-largest city in the United States. Discover San Diego’s distinctive neighborhoods on a San Diego shore excursion. Visit Old Town, North Park, Point Loma and Coronado are all within a few miles of the port, while the bustling Gaslamp Quarter and Little Italy are within walking distance.

And while there are lots of things to do for everyone on a San Diego Cruise—from visiting the country’s largest urban park to taking in the famous horse-racing season in Del Mar to riding the charming Old Town Trolley—definitely don’t pass up the chance to investigate San Diego’s quickly growing reputation as a culinary destination. Its inventive new restaurants and huge craft-brewing industry are something to be explored.